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在视网膜血管发育和血脑屏障可塑性中的诺林/Frizzled4信号传递

Yanshu Wang1, Amir Rattner, Yulian Zhou

  • 1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|December 11, 2012
PubMed
概括

诺林/Frizzled4 (Fz4) 信号传递对于视网膜血管发育至关重要. 内皮细胞中缺陷的Fz4信号导致血管缺陷和消除,突出显示了质量控制机制和持续的屏障功能作用.

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