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Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
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中一种MCM复合物的演化,该复合物通过阻断BLM螺旋酶来促进介质交叉

Kathryn P Kohl1, Corbin D Jones, Jeff Sekelsky

  • 1Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|December 11, 2012
PubMed
概括

在中,微染色体维护 (MCM) 蛋白质取代了Msh4-Msh5复合体,以确保介质交叉生成. 这种MCM复合体的演变是为了促进交叉,克服Msh4-Msh5.5的损失.

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