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Updated: May 15, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
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Published on: June 30, 2016

循环GMP-AMP是一种内源的第二信使,通过细胞核DNA传递天生的免疫信号

Jiaxi Wu1, Lijun Sun1,2, Xiang Chen1

  • 1Department of Molecular Biology University of Texas Southwestern Medical Center Dallas, TX 75390-9148.

Science (New York, N.Y.)
|December 22, 2012
PubMed
概括

细胞质DNA触发了一个新的信号通路. 这一途径产生循环GMP-AMP (cGAMP),激活STING并导致用于抗微生物防御的干扰素产生.

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