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生物合成的多任务处理促进了海洋细菌中thalassospiramide结构的多样性

Avena C Ross1, Ying Xu, Liang Lu

  • 1Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|December 29, 2012
PubMed
概括

海洋细菌thalassospira和tistrella产生新的免疫抑制循环脂,thalassospiramides. 这些强大的calpain 1蛋白酶抑制剂由于复杂的生物合成途径而表现出广泛的结构多样性.

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