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Updated: May 15, 2026

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
17:45

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Published on: February 26, 2012

无试验小鼠显示正常的学习和记忆

Anna M Lee1, Benjamin R Kanter, Dan Wang

  • 1Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, 5858 Horton Street, Suite 200, Emeryville, California 94608, USA.

Nature
|January 4, 2013
PubMed
概括

在小鼠中缺少蛋白质激酶M-ζ (PKM-ζ) 并没有影响学习或记忆. 像ZIP这样的药物抑制剂可以消除奖励记忆,即使没有PKM-ζ存在.

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Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis14:58

Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis

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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.