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53BP1通过使用Rif1调节DSB修复,以控制5'末端切除

Michal Zimmermann1, Francisca Lottersberger, Sara B Buonomo

  • 1Laboratory for Cell Biology and Genetics, Rockefeller University, New York, NY 10065, USA.

Science (New York, N.Y.)
|January 12, 2013
PubMed
概括

53BP1通过抑制5'末端切除来控制DNA修复,这是对基因组稳定性至关重要的过程. 这项研究确定Rif1是53BP1的关键调解者.

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