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Updated: May 15, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

通过姓氏推断确定个人基因组.

Melissa Gymrek1, Amy L McGuire, David Golan

  • 1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|January 19, 2013
PubMed
概括

个人基因组可以通过将Y染色体短串重复 (Y-STRs) 与公共家谱数据库联系起来来解除匿名化. 这种方法使用姓氏和元数据,可以在共享的测序数据中识别个人.

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