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基因编码的铜 (I) 记者具有更好的反应,可用于成像

Jun Liu1, Jason Karpus, Seraphine V Wegner

  • 1Beijing National Laboratory for Molecular Sciences, Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Journal of the American Chemical Society
|January 31, 2013
PubMed
概括

研究人员开发了一种新的遗传编码探针,用于监测活细胞内的铜水平. 这种创新工具使用一种经过修改的铜调节蛋白 (Ace1) 与光蛋白融合,以改进铜的检测.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...