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通过蛋白激酶RIPK4对Dishevelled的酸化调节了Wnt信号传递

XiaoDong Huang1, James C McGann, Bob Y Liu

  • 1Department of Physiological Chemistry, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

Science (New York, N.Y.)
|February 2, 2013
PubMed
概括

受体相互作用蛋白激酶4 (RIPK4) 通过稳定β-catenin激活Wnt信号,影响表皮发育,并可能驱动瘤生长. 这一发现揭示了RIPK4的存在.

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