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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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在DNA聚合酶中切换位点的动力学

Rajan Lamichhane1, Svitlana Y Berezhna, Joshua P Gill

  • 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|February 16, 2013
PubMed
概括

DNA聚合酶在DNA合成和校对中使用不同的位点. 这项研究揭示了DNA基质通过分子内和分子间转移在这些位点之间移动,分子内转移更快,提高了DNA修复效率.

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Overview
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