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针对抗体的药物发现

M E Wolff1, A McPherson

  • 1ImmunoPharmaceutics, Inc., San Diego, California 92127.

Nature
|May 24, 1990
PubMed
概括

针对抗体的药物发现利用免疫系统来识别药物配体的目标部位. 这种方法加快了创建新型治疗实体的速度.

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Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...