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Updated: May 13, 2026

Highly Efficient Ligation of Small RNA Molecules for MicroRNA Quantitation by High-Throughput Sequencing
14:15

Highly Efficient Ligation of Small RNA Molecules for MicroRNA Quantitation by High-Throughput Sequencing

Published on: November 18, 2014

自然的RNA圆圈作为高效的microRNA海绵起作用.

Thomas B Hansen1, Trine I Jensen, Bettina H Clausen

  • 1Department of Molecular Biology and Genetics, Aarhus University, C.F. Møllers Alle 3, 8000C, Aarhus, Denmark.

Nature
|March 1, 2013
PubMed
概括

循环RNAs (circRNAs) 可以充当miRNA海绵. 一种新的circRNA,ciRS-7,作为microRNA-7 (miR-7) 的强有力的海绵,影响大脑中的基因表达.

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Single-step Purification of Macromolecular Complexes Using RNA Attached to Biotin and a Photo-cleavable Linker

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RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
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Nucleic Acids02:43

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RNA Interference01:23

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RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
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Ribozymes02:47

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The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
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