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SCF ((FBXL3) 无处不在合酶针对其辅因子口袋中的加密染色体

Weiman Xing1, Luca Busino, Thomas R Hinds

  • 1Department of Pharmacology, University of Washington, Seattle, Washington 98195, USA.

Nature
|March 19, 2013
PubMed
概括

哺乳动物的加密染色体2 (CRY2) 结构揭示了FBXL3如何准CRY2进行降解,从而影响昼夜时钟. 这种由黄胺二核酸 (FAD) 和周期蛋白 (PERs) 影响的相互作用提供了潜在的药物标.

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