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Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
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免疫球蛋白类域的无形蛋白聚合的机械模型

Madeleine B Borgia1, Adrian A Nickson, Jane Clarke

  • 1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.

Journal of the American Chemical Society
|March 21, 2013
PubMed
概括

与阿尔茨海默氏症等疾病相关的蛋白质聚合可能不遵循典型的核化模型. 我们的研究表明,聚合通过激活的二次体发生,其速率取决于聚合面积.

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