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Updated: May 13, 2026

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Published on: May 23, 2025

通过Nutlin-3a激活肺的p53,可以预防和逆转实验性肺高血压

Nathalie Mouraret1, Elisabeth Marcos, Shariq Abid

  • 1Hôpital Henri Mondor, Service de Physiologie-Explorations Fonctionnelles, Créteil, France.

Circulation
|March 21, 2013
PubMed
概括

努特林-3a在肺动脉光滑肌细胞中诱导细胞衰老,通过限制细胞增殖,为肺高血压 (PH) 提供潜在的治疗方法. 这种前性疗法在减少PH严重性和相关并发症方面表现有前途.

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