相关实验视频
Updated: May 13, 2026

08:41
Quantifying Abdominal Pigmentation in Drosophila melanogaster
Published on: June 1, 2017
通过基因调节模块的进化,色素的出现和多样化
Laurent Arnoult1, Kathy F Y Su, Diogo Manoel
1Aix-Marseille Université, CNRS, UMR 7288, Institut de Biologie du Développement de Marseille-Luminy, 13288 Marseille cedex 9, France.
概括
一种新型的基因调节模块使得中出现了黑色的翅膀色素斑点. 这一监管机构的后续变化.
科学领域:
- 进化生物学是进化的生物学.
- 遗传学 是一个遗传学.
- 发育生物学是发展生物学.
背景情况:
- 形态进化往往涉及新的特征的出现和多样化.
- 这些进化步骤的遗传基础,特别是色素,仍然在很大程度上是未知的.
研究的目的:
- 研究在身上翅膀色素化模式的起源和多样化背后的遗传机制.
- 为了确定负责翅膀斑点进化的遗传网络.
主要方法:
- 对基因调控模块组件的分析.
- 研究色素基因及其转录调节者的进化.
- 检查基因表达模式的变化.
主要成果:
- 一个新的基因调节模块促进了暗翼色素斑点的出现.
- 颜色基因被合作选择,以响应共享的转录调节器.
- 机翼斑点模式的多样化是通过调节器表达式的改变而发生的.
结论:
- 用于特征出现和多样化的遗传变化在遗传网络中被隔离.
- 了解基因调节网络是解读进化过程的关键.
- 这项研究为新型特征进化的遗传基础提供了一个模型.
相关概念视频
Gene Duplication and Divergence
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
Position-effect Variegation
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
Epistasis
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Background and Environment Affect Phenotype
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Evolution of New Traits in Microbes
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...

