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Updated: May 12, 2026

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一个DNAzyme-黄金纳米粒子探针在活细胞中寻找乌兰离子

Peiwen Wu1, Kevin Hwang, Tian Lan

  • 1Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

Journal of the American Chemical Society
|March 28, 2013
PubMed
概括

这项研究引入了第一个用于检测细胞内部金属离子的DNA酶传感器. 这种基于金纳米粒子的新型探测器可以实时监测细胞内金属离子.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...