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通过MATE多药物传送器的药物挤出机制的结构基础

Yoshiki Tanaka1, Christopher J Hipolito, Andrés D Maturana

  • 1RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.

Nature
|March 29, 2013
PubMed
概括

研究人员阐明了一个关键的多药物和有毒化合物挤出 (MATE) 载体的结构,揭示了药物挤出机制,并确定了用于治疗应用的强效抑制剂.

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