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Updated: May 1, 2026

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扩大可复制的非自然DNA的范围:逐步优化一种主要是疏水的基对

Thomas Lavergne1, Mélissa Degardin, Denis A Malyshev

  • 1Department of Chemistry and Center for Protein and Nucleic Acid Research, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|April 4, 2013
PubMed
概括

研究人员通过创造新的疏水性非自然基因对来扩展遗传字母. 最有前途的衍生品d5SICS-dFEMO显示了增强的复制效率和真实性,为体内应用铺平了道路.

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