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相关概念视频

Vision01:24

Vision

48.7K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
48.7K
Neural Circuits01:25

Neural Circuits

3.0K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.0K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

8.1K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
8.1K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

8.6K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
8.6K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.5K
Visual System01:26

Visual System

2.3K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
2.3K

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相关实验视频

Updated: May 6, 2026

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging
11:24

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging

Published on: December 12, 2012

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在视觉皮层中出现功能性微电路.

Ho Ko1, Lee Cossell, Chiara Baragli

  • 1Department of Neuroscience, Physiology and Pharmacology, University College London, 21 University Street, London WC1E 6DE, UK.

Nature
|April 5, 2013
PubMed
概括

新形成的皮层电路连接神经元,在眼睛打开后具有类似的视觉反应. 这表明感官处理的顺序发展,优先考虑特征选择性,而不是精确的局部突触组织.

科学领域:

  • 神经科学是一个神经科学.
  • 发育神经科学的发展神经科学.
  • 系统神经科学 系统神经科学

背景情况:

  • 新皮层微电路具有结构化的突触连接,用于感觉处理.
  • 功能性组织的皮质微电路的发展基础尚未完全理解.

研究的目的:

  • 研究小鼠视觉皮层中功能连接的发育机制.
  • 为了将突触连接模式与神经元在发育过程中的视觉响应特性相关联.

主要方法:

  • 在体内进行两光子成像.
  • 在实验室中,从2/3层的金字塔神经元中记录了多个全细胞.
  • 分析不同出生后年龄的激发性突触连接性和视觉反应选择性.

主要成果:

  • 神经元反应在眼睛打开时是有选择的,但类似反应的神经元之间的优先连接后来出现了.
  • 当地连接在眼睛开放后进行了重组,增加了视觉响应神经元之间的选择性连接,并消除了不响应神经元之间的连接.
  • 在整个开发过程中,整体连接率保持稳定.

结论:

  • 视觉特征选择性的出现并不取决于眼睛打开时的精确局部突触安排.

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Visualization of Cortical Modules in Flattened Mammalian Cortices

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Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping

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相关实验视频

Last Updated: May 6, 2026

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging
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Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging

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Visualization of Cortical Modules in Flattened Mammalian Cortices
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Visualization of Cortical Modules in Flattened Mammalian Cortices

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  • 皮层微电路的发展遵循一个顺序模型:神经元通过前输入获得特征偏好,潜在的辅助电气合,在感官体验之前.
  • 然后,有模式的感官输入通过活动依赖的可塑性和反复发生的突触连接的重新分配来驱动功能子网络的形成.