儿童偏头痛与婴儿史之间的关联
Silvia Romanello1, Daniele Spiri, Elena Marcuzzi
1Department of Pediatric Emergency Care, APHP-Hospital Robert Debré, Paris, France.
JAMA
|April 18, 2013
概括
被诊断为偏头痛的儿童更有可能有婴儿结肠的病史. 这表明,在儿科患者群体中,早期疼痛和晚期偏头痛发展之间存在潜在的联系.
科学领域:
- 儿科神经学 儿科神经学
- 疼痛综合征 疼痛综合征
- 流行病学 流行病学
背景情况:
- 婴儿大肠是一种常见的疾病,会导致婴儿无法安慰的哭泣,通常被认为是一种疼痛综合征.
- 偏头痛是儿童头痛的常见原因之一.
- 婴儿结肠和儿童偏头痛之间的潜在关联仍然未被探索.
研究的目的:
- 调查婴儿结肠和儿童中偏头痛的发展之间可能存在的关联.
- 为了确定婴儿结肠的病史是否在被诊断为偏头痛的儿童中更常见.
主要方法:
- 一项涉及208名被诊断患有偏头痛的儿童 (年龄在6-18岁) 和471名被诊断患有轻微创伤的儿童 (年龄在6-18岁) 的病例控制研究.
- 通过结构化问卷收集婴儿结肠史数据,并通过健康小册子确认.
- 一项二次研究包括120名患有紧张型头痛的儿童,以评估观察到的关联的特异性.
主要成果:
- 与对照组 (26.5%) 相比,患有偏头痛的儿童患有婴儿结肠史的患病率显著更高 (72.6%),几率比率为6.61 (95% CI,4.38-10.00).
- 这种关联在偏头痛有光环和偏头痛没有光环亚型中都是一致的.
- 婴儿和张力型头痛之间没有发现显著的关联 (OR,1.46;P = .10).
结论:
- 婴儿史与儿童和青少年中偏头痛的存在有显著的关联.
- 这些发现表明,早期生活中的疼痛经历和偏头痛的后期发展之间存在潜在的联系.
- 需要进一步的纵向研究来证实这种关联并探索潜在的机制.
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