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神经元再生的发育性下降是由于两个内在定时器的逐渐变化导致的

Yan Zou1, Hui Chiu1, Anna Zinovyeva2

  • 1Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, Ohio 45229.

Science (New York, N.Y.)
|April 20, 2013
PubMed
概括

老化Caenorhabditis elegans神经元由于let-7微RNA抑制LIN-41而失去轴突再生能力. 这种互惠的let-7-LIN-41电路确保再生仅在老年神经元中被阻止.

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