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Updated: May 12, 2026

Novel RNA-Binding Proteins Isolation by the RaPID Methodology
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Published on: September 30, 2016

基于机制的三氨酸探针用于捕获内源性RSNO

Uthpala Seneviratne1, Luiz C Godoy, John S Wishnok

  • 1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|April 26, 2013
PubMed
概括

新的氨酸探针能够直接和具体检测氧化物 (RSNO),这是氧化 (NO) 代谢和信号传递中的关键分子. 这一突破为研究与NO相关的生物过程和疾病提供了可靠的工具.

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...