评论"在做出基于价值的决策的子中,LIP神经元编码的提示突出,而不是行动价值"
William T Newsome1, Paul W Glimcher, Jacqueline Gottlieb
1Department of Neurobiology and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
概括
利瑟斯和奥尔森得出的结论是,子侧侧内皮 (LIP) 区域的神经元只编码提示突出,而不是行动值. 这一结论是有问题的,因为时间分析有限,无法复制已建立的LIP生理学.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 决策神经科学 决策神经科学
背景情况:
- 侧侧内皮层 (LIP) 皮层区域涉及基于价值的决策.
- 之前的研究表明,LIP神经元编码动作值和暗示突出.
研究的目的:
- 批判性地评估Leathers和Olson (2012) 在决策过程中关于LIP神经元活动的结论.
- 为了解决原始研究中的时间范围和生理复制问题.
主要方法:
- 在行为任务期间,分析LIP区域的神经元反应.
- 观察到的生理特征与LIP中先前确定的发现进行比较.
主要成果:
- 利瑟斯和奥尔森的主要结论是基于有限的早期审判时代,而不是整个决策过程.
- 该研究未能复制其他实验室在随后的时间时代报告的LIP神经元的关键生理特征.
结论:
- 广泛的结论是,LIP神经元在决策过程中专门编码暗示突出性的广泛结论并未得到充分支持.
- 关于时间分析和复制的方法限制引起了对原始研究结果的担忧.
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