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揭示了催化氧环素生物合成的最后步骤的酶

Peng Wang1, Ghader Bashiri, Xue Gao

  • 1Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California 90095, USA.

Journal of the American Chemical Society
|April 30, 2013
PubMed
概括

两种新的氧化还原酶,OxyS和OxyR,通过催化关键的氧化和还原步骤,完成了氧化四环素的生物合成. 这项研究阐明了生产这种重要的广谱抗生素的最终酶途径.

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