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Updated: May 11, 2026

Proofreading and DNA Repair Assay Using Single Nucleotide Extension and MALDI-TOF Mass Spectrometry Analysis
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Published on: June 19, 2018

在你的标志上,得到SET (D2),去! H3K36me3素数DNA不匹配的修复

Christine K Schmidt1, Stephen P Jackson

  • 1The Gurdon Institute and the Department of Biochemistry, University of Cambridge, Cambridge, UK.

Cell
|April 30, 2013
PubMed
概括

通过SETD2对Lys36 (H3K36me3) 上的希斯H3的三甲基化有助于DNA修复. 这一发现解释了MMR缺陷癌症,通过展示H3K36me3如何准修复机械到染色素.

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