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通过ADP-ribosylation调节蛋白质酶的调节

Park F Cho-Park1, Hermann Steller

  • 1Strang Laboratory of Apoptosis and Cancer Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA.

Cell
|April 30, 2013
PubMed
概括

ADP-ribosylation通过修改PI31,一个调节器来增强26S蛋白酶体活性. 这个过程涉及坦基酶 (TNKS),并促进26S蛋白质组的组装,这对细胞存活至关重要,并且与疾病有关.

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