耳鼻面部节奏的层次结构通过和呼吸来揭示
Jeffrey D Moore1, Martin Deschênes, Takahiro Furuta
1Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
Nature
|April 30, 2013
概括
动物的和嗅觉行为是由腹髓中的呼吸中心协调的. 这种神经回路确保面部运动 (如) 与呼吸模式同步.
科学领域:
- 神经科学是一个神经科学.
- 行为生物学 行为生物学
- 发动机控制器的控制器
背景情况:
- 和嗅觉是动物的关键探索行为.
- 协调这些或面部运动模式的神经机制尚不清楚.
研究的目的:
- 为了研究神经控制协调的和嗅觉行为.
- 确定负责产生和同步这些运动与呼吸的大脑区域.
主要方法:
- 解剖学上的追踪技术.
- 动物探索行动的行为分析.
- 神经元活动的电生理记录.
- 对神经回路的药理学操纵.
主要成果:
- 确定了一个特定的腹髓区域,可以节奏地驱动vibrissae延伸.
- 证明Bötzinger前综合体在灵感过程中从这个区域重置神经元输出.
- 建立了呼吸循环和鞭打/嗅探协调之间的直接联系,在高频嗅探时存在一对一的关系.
结论:
- 腹中髓中的呼吸中心协调和嗅.
- 博辛格前综合体作为一个关键的定时信号,对 orofacial 运动模式.
- 呼吸核可以作为呼吸协调行为的主钟.
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