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Updated: May 11, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

作为人工基对用于DNA双重复合的光交叉链接的p-stilbazole部分

Hiromu Kashida1, Tetsuya Doi, Takumi Sakakibara

  • 1Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan. kashida@nubio.nagoya-u.ac.jp

Journal of the American Chemical Society
|May 7, 2013
PubMed
概括

研究人员使用p-stilbazole人工基对开发了一种用于DNA的新型光交联反应. 这种方法快速稳定DNA复合体,为先进的纳米材料提供了潜力.

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Phosphodiester Linkages

Overview
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DNA Base Pairing

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Base-pairing and DNA Repair

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Single-Strand DNA Binding Proteins

For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
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Labeling DNA Probes

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Long-patch Base Excision Repair

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