在心中年轻,心中年轻
Leslie A Leinwand1, Brooke C Harrison
1Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado at Boulder, Boulder, CO 80309, USA. leslie.leinwand@colorado.edu
Cell
|May 14, 2013
概括
年轻小鼠的血液循环可以逆转老小鼠的心脏缩. 这种效应通过用生长分化因子11 (GDF11) 对老老鼠进行治疗来复制,这表明GDF11治疗与年龄有关的心脏病.
科学领域:
- 老年学和再生医学的研究.
- 心血管生物学 心血管生物学
背景情况:
- 衰老与心脏结构和功能的有害变化有关,包括心脏缩.
- 与年龄相关的心脏缩会损害心脏功能,增加心血管疾病的风险.
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