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Updated: May 11, 2026

Sensitive Measurement of Mitophagy by Flow Cytometry Using the pH-dependent Fluorescent Reporter mt-Keima
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Published on: August 12, 2018

线粒体守门人酸盐脱酶在瘤基因诱导的衰老中起着关键作用

Joanna Kaplon1, Liang Zheng, Katrin Meissl

  • 1Division of Molecular Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Nature
|May 21, 2013
PubMed
概括

瘤基因诱导衰老 (OIS) 通过阻止细胞增殖来预防癌症. 这项研究揭示了酸盐脱酶 (PDH) 是OIS的关键,它将新陈代谢与癌症抑制联系起来,并为黑色素瘤提供了新的治疗点.

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