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Updated: May 11, 2026

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
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Published on: April 18, 2016

在ER中,虚无蛋白质折叠周期由未折叠的蛋白质O-曼诺基化通路终止

Chengchao Xu1, Songyu Wang, Guillaume Thibault

  • 1Temasek Life Sciences Laboratory, National University of Singapore, Singapore.

Science (New York, N.Y.)
|May 25, 2013
PubMed
概括

通过O-mannosylation,一种糖的修饰,可以终止内质网膜 (ER) 中的蛋白质折叠. 这一过程防止错误折叠的蛋白质消耗细胞资源,并促进它们的降解.

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