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Updated: May 11, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
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Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

通过胺-以基突变检测骨干键在蛋白质-基相互作用中的作用

Jonas N N Eildal1, Greta Hultqvist, Thomas Balle

  • 1Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

Journal of the American Chemical Society
|May 28, 2013
PubMed
概括

脊柱键对于将连接体与后突触密度95/大盘/封闭区1 (PDZ) 域结合至关重要. 扰乱这些键会显著影响结合亲和力,揭示它们在蛋白质-相互作用中的重要性.

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