血液输血的替代方案 输血的替代方案
Donat R Spahn1, Lawrence T Goodnough
1Institute of Anaesthesiology, University and University Hospital Zurich, Zurich, Switzerland. donat.spahn@usz.ch
由于风险和成本,异构输血的替代品越来越受青. 患者的结果和成本效益将推动在治疗贫血时采用血液替代品.
科学领域:
- 输血医学 输血医学
- 贫血管理 贫血管理
背景情况:
- 全基因输血具有固有的风险和重大成本.
- 医疗保健系统面临的挑战是血液库存管理和输血相关的不良结果.
研究的目的:
- 审查血液输血替代品在治疗医疗和外科手术性贫血中的当前作用.
- 评估各种血液替代品的成本效益概况和风险效益概况.
主要方法:
- 关于输血替代方案的研究文献综述.
- 对血液储存策略的成本效益和风险效益数据的分析.
主要成果:
- 有证据表明,由于成本和不良结果,血液使用量有所下降.
- 成本和患者的结果是采用血液替代品的关键驱动因素.
- 正在研究自身血液,红色受体刺激剂和静血剂的风险益处概况.
结论:
- 随着血液成本的上升和内在的输血风险,支持血液替代品的持续开发和使用.
- 代替输血的替代方法对于有效管理医疗和手术性贫血至关重要.
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