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增强剂RNAs对于雌激素依赖的转录激活的功能性作用

Wenbo Li1, Dimple Notani, Qi Ma

  • 1Howard Hughes Medical Institute, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA.

Nature
|June 4, 2013
PubMed
概括

增强器RNAs (eRNAs) 从增强器转录,并在基因调节中发挥功能作用. 这项研究表明,17β-雌醇 (E2) 诱导eRNAs,增强雌激素受体α (ER-α) 目标基因激活在乳腺癌细胞.

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