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Updated: May 10, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

使用大规模量子化学计算推导的不同DNA guanine四重复干拓的相对稳定性

Jiří Šponer1, Arnošt Mládek, Naďa Špačková

  • 1Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 612 65 Brno, Czech Republic. sponer@ncbr.muni.cz

Journal of the American Chemical Society
|June 8, 2013
PubMed
概括

这项研究使用了精确的量子力学 (QM) 计算来预测瓜四重复 (G-DNA) 结构的稳定性. 与标准分子力学力场相比,QM计算揭示了显著的差异,改善了G-DNA干稳定性的理论预测.

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