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Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
16:01

Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis

Published on: January 26, 2015

mast细胞作为预制和免疫可诱导TNF-alpha/cachectin的来源

J R Gordon1, S J Galli

  • 1Department of Pathology, Beth Israel Hospital, Boston, Massachusetts 02215.

Nature
|July 19, 1990
PubMed
概括

鼠标肥肉细胞组成性地产生和释放瘤缩因子-α (TNF-α). 依赖IgE的激活增强了这种释放,识别了巨细胞作为TNF-alpha参与宿主防御和过敏疾病的关键来源.

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