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在成年人中,海马神经发生的动力学

Kirsty L Spalding1, Olaf Bergmann1, Kanar Alkass1,2

  • 1Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.

Cell
|June 11, 2013
PubMed
概括

成年海马神经发生发生在人类中,每天每海马产生700个新神经元. 这表明成人海马神经发生有助于人类大脑功能和认知可塑性.

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Neurogenesis and Regeneration of Nervous Tissue01:15

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...