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终结MT有助于大脑洞腔形的发病和进展

Luigi Maddaluno1, Noemi Rudini, Roberto Cuttano

  • 1IFOM Fondazione, FIRC Institute of Molecular Oncology, 20139 Milan, Italy. uigi.maddaluno@ifom.eu

Nature
|June 11, 2013
PubMed
概括

大脑洞腔形 (CCM) 是由CCM基因突变引起的脑血管缺陷. 这项研究表明,阻断TGF-β和BMP信号,可以防止内皮细胞转移到介质细胞,从而减少CCM病变的发生.

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