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Updated: May 10, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

非洲裔美国人与华法林剂量相关的遗传变异:全基因组关联研究研究

Minoli A Perera1, Larisa H Cavallari, Nita A Limdi

  • 1Section of Genetic Medicine, Department of Medicine, University of Chicago, IL, USA.

Lancet (London, England)
|June 13, 2013
PubMed
概括

一种新的基因变异,CYP2C中的rs12777823,显著影响了非洲裔美国人的华法林剂量. 这一发现改善了华法林剂量预测,超出了已知的基因,如VKORC1和CYP2C9.

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