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Updated: May 10, 2026

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NLRC4的晶体结构揭示了其自身抑制机制

Zehan Hu1, Chuangye Yan, Peiyuan Liu

  • 1School of Life Sciences, Tsinghua University, and Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.

Science (New York, N.Y.)
|June 15, 2013
PubMed
概括

核酸结合和寡聚化域类受体 (NLR) 蛋白质,如NLRC4,使用一种新的自身抑制机制. 这涉及域间的相互作用,使NLRC4保持不活跃,直到特定的信号触发其激活.

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