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Updated: May 10, 2026

An Electrochemiluminescence-Based Assay for MeCP2 Protein Variants
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MeCP2 threonine 308的活性依赖酸化调节了与NCoR的相互作用

Daniel H Ebert1, Harrison W Gabel, Nathaniel D Robinson

  • 1Department of Neurobiology, Harvard Medical School, and Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

Nature
|June 18, 2013
PubMed
概括

雷特综合征 (RTT) 与甲基-CpG结合蛋白2 (MeCP2) 突变有关. MeCP2在T308的活性依赖酸化调节基因表达和与共抑制剂的相互作用,其损失可能导致RTT.

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