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血清转化到多个小岛自身抗体和儿童糖尿病进展的风险

Anette G Ziegler1, Marian Rewers, Olli Simell

  • 1Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Ingolstaedter Landstrase 1, Neuherberg, Germany 85764. anette-g.ziegler@helmholtz-muenchen.de

JAMA
|June 20, 2013
PubMed
概括

大多数患有多个小岛自身抗体的儿童在15年内会患上1型糖尿病. 早期血清转化 (3岁以下),特定的HLA基因型,以及女性增加这种风险. 预防工作应该针对这个高风险群体.

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