在成人中进行一般健康检查,以减少因疾病引起的发病率和死亡率
Lasse T Krogsbøll1, Karsten Juhl Jørgensen, Peter C Gøtzsche
1Nordic Cochrane Centre, Rigshospitalet Department 7811, Blegdamsvej 9, 2100 København Ø, Denmark. ltk@cochrane.dk
JAMA
|June 20, 2013
概括
成人的一般健康检查并不能降低所有原因,心血管疾病或癌症的死亡率. 然而,它们可能会导致诊断和药物治疗的增加,不经常报告危害.
科学领域:
- 预防医学 预防医学
- 公共卫生干预措施 公共卫生干预措施
- 临床有效性研究研究临床有效性研究
背景情况:
- 一般健康检查被广泛提供给成年人群.
- 关于它们的益处和危害的证据仍在争论中.
- 了解这些检查的影响对于医疗保健政策至关重要.
研究的目的:
- 评估成年人群的一般健康检查的益处和危害.
- 确定健康检查与死亡率和发病率的关联.
- 评估诊断程序和药物治疗的发生率.
主要方法:
- 随机对照试验的系统审查和元分析.
- 包括比较医疗检查与常规护理服务的研究.
- 评估结果,包括全因死亡率,疾病特异性死亡率,发病率和危害.
主要成果:
- 提供健康检查并没有与所有原因死亡率的降低有关.
- 没有观察到从心血管疾病或癌症死亡率的显著降低.
- 健康检查与诊断和药物处方增加有关.
- 发病率和危害,如诊断程序,很少被报告.
结论:
- 一般健康检查似乎没有降低成年人群的死亡率.
- 有可能增加医疗干预,包括诊断和药物治疗.
- 需要进一步的研究才能充分阐明长期的危害和益处.
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