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-合金合作性N-H键激活和脱联的一个例子

Thomas W Myers¹, Louise A Berben

¹Department of Chemistry, University of California, Davis, California 95616, USA.

Journal of the American Chemical Society

|June 27, 2013

概括

这项研究详细介绍了分子复合物如何使用金属连接体合作来激活N-H键. 这一过程使新的化学转化和催化应用成为可能.

科学领域:

有机金属化学有机金属化学
催化剂是一种催化剂.
无机化学无机化学

背景情况:

金属-联体合作是有机金属化学中激活小分子的关键策略.
复合物,特别是那些含有多牙连接体的复合物,具有独特的反应性.
了解NH键激活对于开发新的合成方法至关重要.

研究的目的:

描述分子复合物的N-H键的激活.
通过金属-合金合作来研究N-H键激活的机制.
探索复合物的催化潜力在脱联接反应中.

主要方法:

合成和特征的三酸 bis (((imino) 皮里丁化复合物.
复合物的与素的反应形成N-H活性产物.
激活产品的热处理以研究后续的转化.
复合物的催化评估在基胺的脱配合中.

主要成果:

复合物 ((Ph) I2P(2-))AlH (1b) 成功激活了线中的N-H键,产生了N-H激活产物 ((Ph) HI2P(-))AlH(NHAr) (2).
加热中间体2导致H2的释放,并形成胺复合物 ((Ph) I2P(-)) Al(NHAr) (3).
复合物1b在zylamine的脱配合中表现出催化活性,产生,氨和一种 imine.

结论:

具有三酸 (酸) 胺连接体的分子复合体可以通过金属连接体合作来激活N-H键.
观察到的转变突出显示了N-H键功能化和随后的催化脱的途径.
这项工作扩大了介导催化和N-H键激活策略的范围.

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