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Updated: May 10, 2026

Characterizing Multidrug Efflux Systems in Acinetobacter baumannii Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System
05:06

Characterizing Multidrug Efflux Systems in Acinetobacter baumannii Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

Published on: January 5, 2024

抑制细菌多种药物出口者的结构基础

Ryosuke Nakashima1, Keisuke Sakurai, Seiji Yamasaki

  • 1Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.

Nature
|July 2, 2013
PubMed
概括

皮里多皮里米丁衍生物通过与疏水陷结合来阻断多药物排放AcrB和MexB,从而阻碍它们的功能. 这一发现有助于开发新的抗生素来对抗格兰氏阴性病原体.

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Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein10:43

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