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Updated: May 9, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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通过调节内皮TGF-β信号传递,LRG1促进血管生成

Xiaomeng Wang1, Sabu Abraham1, Jenny A G McKenzie1

  • 1Department of Cell Biology, UCL Institute of Ophthalmology, London EC1V 9EL, UK.

Nature
|July 23, 2013
PubMed
概括

富含白的α-2-糖蛋白1 (Lrg1) 通过与转化生长因子-β1 (TGF-β1) 相互作用,促进病态血管生成. 抑制Lrg1显著降低了眼球血管生成,揭示了它作为一个新的治疗点.

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