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相关概念视频

Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Cell Diversity01:13

Cell Diversity

The concept of a cell started with microscopic observations of dead cork tissue by Robert Hooke in 1665. Hooke coined the term "cell" based on the resemblance of the small subdivisions in the cork to the rooms that monks inhabited, called cells. About ten years later, Antonie van Leeuwenhoek became the first person to observe the living and moving cells under a microscope. In the century that followed, the theory that cells represented the basic unit of life developed.
Multicellular organisms...
Cellular Differentiation00:57

Cellular Differentiation

How does a complex organism such as a human develop from a single cell? It all starts from a single fertilized egg which gives rise to a vast array of cell types, such as nerve cells, muscle cells, and epithelial cells that characterize the adult? Throughout development and adulthood, cellular differentiation leads cells to assume their final morphology and physiology. Differentiation is the process by which unspecialized cells become specialized to carry out distinct functions.
A zygote is a...
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
Non-equilibrium in the Cell01:16

Non-equilibrium in the Cell

An important concept in studying metabolism and energy is that of chemical equilibrium. Most chemical reactions are reversible. They can proceed in both directions, releasing energy into their environment in one direction, and absorbing it from the environment in the other direction. The same is true for the chemical reactions involved in cell metabolism, such as the breaking down and building up of proteins into and from individual amino acids, respectively. Reactants within a closed system...

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相关实验视频

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Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells
15:41

Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells

Published on: December 2, 2010

微分几何满足了细胞的结构.

Wallace F Marshall1

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco, 600 16th Street, San Francisco, CA 94158, USA. wallace.marshall@ucsf.edu

Cell
|July 23, 2013
PubMed
概括

物理力量塑造生物结构. 细胞内的连接形成了螺旋形,这是膜物理学的可预测结果.

科学领域:

  • 细胞生物学 细胞生物学
  • 生物物理学的生物物理.
  • 数学生物学 数学生物学

背景情况:

  • 细胞内膜网膜是参与蛋白质和脂质合成的关键器官.
  • 控制细胞结构的精确排列的物理力量尚未完全理解.
  • 细胞内堆叠的膜结合的囊,称为水箱,表现出特定的组织模式.

研究的目的:

  • 为了研究构成堆叠的内质网膜水瓶的物理原理.
  • 确定经典微分几何学的几何形状是否与生物结构相关.
  • 阐明膜物理在确定细胞形态学中的作用.

主要方法:

  • 对堆叠的内等质网膜水瓶之间的连接的几何形状的分析.
  • 应用经典微分几何原理来描述观察到的形状.
  • 模拟膜物理来预测这些结构的形成.

主要成果:

  • 堆叠的内等质网膜水箱之间的连接被确定为具有状的形状.
  • 这种螺旋形状是古典微分几何学中一个成熟的几何形状.
  • 观察到的形状是细胞膜物理性质的可预测结果.

结论:

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Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps
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Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells
15:41

Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells

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A Microfluidic Technique to Probe Cell Deformability
09:47

A Microfluidic Technique to Probe Cell Deformability

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Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps
08:59

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps

Published on: October 28, 2018

  • 物理力量,特别是膜物理,在确定生物形式方面发挥着至关重要的作用.
  • 状形状的内质网膜水箱连接不是任意的,而是受物理定律的支配.
  • 这项研究结合了古典几何学和细胞生物学,为细胞架构的物理基础提供了洞察力.