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Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
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通过激活线粒体UPR和FOXO信号传导,NAD(+) /Sirtuin通路调节长寿

Laurent Mouchiroud1, Riekelt H Houtkooper, Norman Moullan

  • 1Laboratory for Integrative and Systems Physiology, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

Cell
|July 23, 2013
PubMed
概括

降低NAD ((+) 影响衰老和寿命. 通过激活应激反应通路,恢复虫中的NAD () +水平可以促进长寿,这表明与年龄相关的衰退的治疗目标.

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