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Updated: May 9, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
10:59

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

核PTEN控制DNA修复和对基因毒性压力的敏感性

C Bassi1, J Ho, T Srikumar

  • 1Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada.

Science (New York, N.Y.)
|July 27, 2013
PubMed
概括

SUMOylation控制核PTEN定位,这对于DNA损伤反应至关重要. 核PTEN的损失增加了对基因毒性压力的敏感性,影响了癌症治疗策略.

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